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Enzymatic conditions, including eosinophil peroxidase [117], myeloperoxidase [119], and lignin peroxidase [120] accelerate the process through enzymatic digestion

Further optimization established TFE as the best solvent for this transformation, providing the para -aminated phenol in 84% isolated yield (Supplementary Table 2)

Yes, lyophilized peptides can degrade even in powder form, though much more slowly than reconstituted solutions

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These findings position Rh2-O as a candidate for liver cancer therapy and 2-Deoxy-Rh2 for breast cancer treatment (100, 101)