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A comparisonage group adjustedof the data of our patient population with the comparison group from the general population (DAK-insured persons) with at least one drug prescription before the diagnosis of non-melanoma skin cancer showed no significant difference between the two groups ( p = 0.083)
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As male mice more robustly develop symptoms of metabolic syndrome than female, only male Ctrl and KO mice were challenged with a 60% high fat diet (D12492, HFD, Research Diets, New Brunswick, USA) for 12 weeks, starting at the age of 5 weeks, before p53 ablation was facilitated by treating the mice with Tamoxifen (100 mg/kg via oral gavage for 5 consecutive days (Molekula group, Munich, Germany) followed by a 1 week wash out period
