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Key features of the quantitation of semaglutide using the SCIEX 7500 system Low-ng/mL level quantitation of a high-potency GLP-1 analog: Achieve a 0.2 ng/mL LLOQ for semaglutide in rat plasma on the SCIEX 7500 system Ideal analytical performance: Achieve accurate quantitative performance with %CV 0.99

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The idea is supported by maintenance of functional GSH/GSSG levels by Sp in BSO and neurotoxin treated cells as compared to untreated ones which showed a significant decline in the antioxidant ratio probably, due to enhanced formation of glutathionequinones 43