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The dosing of Epitalon was based on a 15-year study done in Russia

Similarly, in the United Kingdom Prospective Diabetes Study (UKPDS), only 34% of patients attained an A1c age 65) and patients with hepatic or renal disease are more likely to experience frequent and severe hypoglycemic reactions, particularly if the goals of therapy aim for inappropriately tight glycemic control (20)

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The role of selenium and prebiotics aimed at normalizing the intestinal microflora in the treatment of GD is considered in this review [52]