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doi: 10.1210/clinem/dgaa863 16 WillardFSDourosJDGabeMBShowalterADWainscottDBSuterTMet al

This isnt required, but it can smooth the screening process

Short, separate studies of individual components in narrow populations have not raised dramatic signals, but that is not the same as demonstrated safety for a fixed four-peptide injectable used repeatedly over time