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While the research is mixed, this meta-analysis on the impact of L-carnitine supplementation on weight loss and body composition concluded that: L-carnitine supplementation provides a modest reducing effect on body weight, BMI and fat mass, especially among adults with overweight/obesity . Therefore, those pursuing fat loss seek out L-carnitine supplements marketed as fat burners to help them achieve their goals

Fatty-acid side chains and other structural modifications can complicate both synthesis and downstream purification

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