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They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]

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About the author Medical Director Aesthetic & Regenerative Medicine Leading Silk Clinics with years of experience in aesthetic medicine, Dr Ahmad Sadeqyar oversees clinical excellence across all departments and personally treats complex aesthetic cases

Immunity 39, 443453

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