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It is suggested that positive dexamethasone suppression test in a patient without high pre-test probability for Cushing's syndrome be repeated without coadministration of GLP1RA or be supported by additional screening tests for Cushings syndrome

Background and aims: Previously reported MODY genes lack crucial gene-level evidence of causality, where rare variants show enrichment in disease cohorts compared to controls

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Nanoformulations, including nanoparticles, liposomes, micelles, and hydrogels, are designed to target the distinct microenvironment of inflamed joints, which is characterized by leaky vasculature, a mildly acidic pH (~6.0), and elevated reactive oxygen species (ROS), to improve therapeutic efficacy (9)