[Learn more about Zepbound] Oral Wegovy (oral semaglutide) For patients who prefer a GLP-1 pill for weight loss over an injection, oral Wegovy is the first oral GLP-1 approved for weight management
Ive really only mentioned the biggest con of GLP-1 agonists which is a potential risk of thyroid cancer but there are others to consider such as muscle loss as well
HCGs biological role is mainly to keep the corpus luteum during early pregnancy
Zhang Y, Chen H, Feng Y, Liu M, Lu Z, Hu B, Chen L, Zhang Y, Liu J, Cai F, Zhao Y, Pan W, Liao X, Pan S, Bestard-Lorigados I, Wu Y, Song W (2025) Activation of AMPK by GLP-1R agonists mitigates Alzheimer-related phenotypes in transgenic mice
Abbreviations AHU: Asymptomatic hyperuricemia MS: Mass spectrometry DBS: Dried blood spot Orn: Ornithine His: Histidine Pip: Piperamide C0: Free carnitine C2: Acetylcarnitine C3: Propionylcarnitine Gly: Glycine C4: Butyrylcarnitine C16: Palmitoylcarnitine MSU: Monosodium urate SUA: Serum uric acid GC: Gas chromatography LC: Liquid chromatography AGA: Acute gout arthritis QC: Quality control PCA: Principal component analysis PLS-DA: Partial least squares discriminant analysis VIP: Variable importance in projection FDR: False discovery rate ROC: Receiver-operating characteristic AUC: Area under the ROC curve BMI: Body-Mass Index LDL: Low density lipoprotein SBP: Systolic blood pressure DBP: Diastolic blood pressure AST: Aspartate aminotransferase ALT: Alanine aminotransferase HDL: High density lipoprotein eGFR: Estimated glomerular filtration rate Thr: Threonine Trp: Tryptophan Pro: Proline Tyr: Tyrosine C5: Isovalerylcarnitine Arg: Arginine Cit: Citrulline Ala: Alanine Phe: Phenylalanine Asn: Asparagine Glu: Glutamic Val: Glutamic Leu: Leucine Ser: Serine MRP4: Multidrug resistance protein 4 BCRP: Breast cancer resistance protein BCAA: Branched chain amino acid Cys: Cysteine OTCD: Ornithine transcarbamylase deficiency CACT: Carnitine-acylcarnitine translocase References Towiwat P, Chhana A, Dalbeth N
