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g , Top five most enriched functional terms for the 1518 differentially expressed genes that were downregulated following GLP-1MK-801 treatment relative to vehicle
Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide are growth factors that can cross the bloodbrain barrier GLP-1 and GIP are peptide hormones and growth factors that play important physiological signaling roles to control cell metabolism and energy utilization (Usdin et al., 1993
It is still a full agonist for all 3 receptors but it is selective for AMY1 so it is more likely to bind to this receptor while having more muted effects on the other two
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Heres how to support natural GLP-1 production every day: Eat protein-rich meals Protein is one of the most effective macronutrients for stimulating GLP-1 secretion
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