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The two main incretins are GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide, previously called gastric inhibitory polypeptide)

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The potential mechanism of action of GLP-1 RAes in MASH may be related to the effects on weight and insulin resistance, as well as reductions in metabolic dysfunction, lipotoxic effects, and inflammation

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