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iHLOs model for toxicology applications To evaluate iHLOs as a model for toxicology studies, we compared proteomic profiles of Day 30 iHLOs, PHHs, HepG2 cells, and HepaRG cells against human liver tissue

Hepcidin is negatively regulated by TMPRSS6, which inhibits hepcidin expression by suppressing Hjv activity and the bone morphogenetic protein-signaling pathway

These results highlight the challenge in specifically measuring mature BDNF due to antibody cross-reactivity

or a history of pancreatitis

The most common are gastrointestinal symptoms, including nausea, vomiting, diarrhea, abdominal pain and constipation