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This effect is mediated by GSH-dependent conjugation and export of anticancer drugs, diminishing their intracellular concentrations and therapeutic efficacy (5053)

However, there was also significant between-design inconsistency (Q=7.09

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For common, non-emergency causes, clinicians can provide prescriptions (for acid suppression, antibiotics when indicated, or short courses of steroids), order appropriate imaging or lab tests, and arrange referrals