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The signal transduction pathways activated by CaSR lead to inactivation of the transporters NKCC2 (encoded by the SLC12A1 gene), ROMK (encoded by the KCNJ1 gene) and Na + /K + -ATPase resulting in decreased reabsorption of Ca 2+ and Mg 2+
Researchers are still studying why this is and what might help treat or prevent these conditions
The body takes in less energy and processes stored energy more efficiently
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