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Approved by the FDA for type 2 diabetes management (as Ozempic and Rybelsus) and chronic weight management (as Wegovy), semaglutide represents a significant advancement in GLP-1-based therapeutics

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Semaglutide is contraindicated in patients with: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Common Adverse Effects According to clinical trial data, gastrointestinal effects are most frequently reported: nausea, vomiting, diarrhea, constipation, and abdominal discomfort