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Similar content being viewed by others Introduction Reduced glutathione (GSH) provides the cellular first line of defense against oxidative stress-induced injury, which can be maintained by NADPH generated mainly via the pentose phosphate pathway and its rate-limiting enzyme, glucose-6-phosphate dehydrogenase (G6PD

When caloric intake drops substantially due to appetite suppression, the body faces a choice about what to burn: stored fat or lean muscle tissue

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