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The authors would like to express their sincere gratitude to the Rheumatology Department at Tanta University Hospital for providing the clinical setting and support for conducting this research

This article demonstrates the efficacy of tirzepatide 5, 10 and 15 mg in people with overweight or obesity without T2D

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The side effect profiles overlap heavily in the GI department, nausea, constipation, reduced appetite, but semaglutide lacks the glucagon receptor activation that gives retatrutide its thermogenic edge

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