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10.1002/adma.202006892 20 GhoshS

Fatigue is listed as a common adverse reaction in FDA prescribing information, occurring in 5% or more of patients taking Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), with higher frequency than placebo in clinical trials

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The limitations of translating these findings into human therapy are increased by the scarcity of clinical data in this context

Patients with active neurological conditions beyond the scope of cognitive optimization should consult their neurologist before adding Dihexa to their protocol