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Key challenges include unresolved long-term biosafety profiles, the absence of standardized large-scale manufacturing protocols, and the insufficient investigation into their potential effects on autophagy and ferroptosis in normal tissues

Remuzzi (IRCCS - Mario Negri Institute for Pharmacological Research, Clinical Research Center for Rare Diseases Aldo e Cele Dacc)

Wild-type mice with femoral fractures show increased CGRP serum levels after injury, and alpha-CGRP mRNA expression is exclusively induced in callus tissue but not in other organs, suggesting a targeted skeletal response

Coconut Oil is a moisturizing ingredient that helps to hydrate the skin and prevent dryness

Future studies will advocate a critical role of oxidative processes on cellular membranes of IECs and decipher the impact of oxidized lipid species in mucosal inflammation and IBD 53,54,55