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Regulator acts to close loophole enabling Australian pharmacists to make copycat Ozempic drug Thu 29 Feb 2024 at 7:06pm , updated Fri 1 Mar 2024 at 4:06pm The Therapeutic Goods Administration (TGA) will move to ban compounding pharmacists from making their own versions of injectable weight loss drugs due to concerns the compounded products may not be safe or effective

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10.1016/0092-8674(93)80066-N Cell 67 HoggN.SinghR

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Or look at Tesofensine, which works centrally in the brain by inhibiting the reuptake of neurotransmitters like dopamine, serotonin, and noradrenaline, thereby influencing appetite and energy expenditure