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It is a term which has often been used to mystify rather than clarify...it is frequently used as a device to cast an aura of legitimacy over the final resolution of policy questions where there are still significant areas of disagreement. (Campbell and Marshall, 2000, p.308) The concept is simultaneously a carrier of many meanings and of no meaning

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While some older GLP-1 agonists required daily dosing (such as liraglutide), the once-weekly formulations now dominate due to their ease of use and sustained effect

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