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GLP-1 drugs might affect mood-related neurotransmitters

This work was supported by the NIH (RC2DK129964 to A.Y.T., R01-DC006982 to L.L

, 2021, vol

Their diet should include a lot of carbohydrates and low fat, where they get their energy from medium-chain triglycerides, that can enter the energy-producing parts of cells even without the presence of a carnitine transport system.

It can change various mitochondrial-related functions, including increasing the production of mitochondrial ROS, reducing mitochondrial transmembrane potential, and changing mitochondrial calcium homeostasis ( in vivo and in vitro through c-Raf and MEK (Figure 5) (Schaedler et al., 2010)