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Frequent shortages have also prompted a booming gray market for compounded GLP-1s, which the FDA has warned can be ineffective and risky

Monitoring includes regular assessment of weight, vital signs, medication tolerance, complete blood count, comprehensive metabolic panel, renal function, and nutritional parameters including vitamin B12, folate, iron, vitamin D, calcium, and protein status

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Safety Profile and Tolerability Concerns Gastrointestinal Adverse Effects While GLP-1RAs are effective in managing obesity, their use is associated with gastrointestinal side effects and rare but serious adverse events [42] [43] [44]