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Bile acids BAs act as pleiotropic signaling molecules that regulate intestinal homeostasis by integrating metabolic, epithelial, and immune pathways through receptor-mediated mechanisms

Typical titration schedule (for Wegovy, for example): Week 14: 0.25 mg once weekly Week 58: 0.5 mg once weekly Week 912: 1.0 mg once weekly and so on, up to the full dose (e.g., 2.4 mg for Wegovy) Each step usually lasts at least 4 weeks to give your body time to adapt

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