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Injectable GHK-Cu was in Category 2 the more restrictive category for substances with "significant safety concerns." Its removal from Category 2 is the more positive development, as it signals the FDA no longer considers injectable GHK-Cu to carry the safety risk level that warranted Category 2 placement

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10.2174/1381612824666180712110447 101 SeiwerthS.SikiricP.GrabarevicZ.ZoricicI.HanzevackiM.LjubanovicD.et al (1997)

Across phase III trials of GLP-1 receptor agonist and multi-hormone receptor modulator obesity drugs in adults with overweight or obesity, the magnitude of blood pressure-lowering was closely associated with the degree of weight loss, highlighting the clinically relevant yet often underappreciated blood pressure-lowering potential of these drugs, the authors concluded

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