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Experiments with human samples were approved by the Research Ethics Committee, the Wako Safety Center in RIKEN (approval number: Wako3 30-4(2))

Based on these facts, it can be concluded that MTF-1 plays a crucial role in maintaining Zn ++ homeostasis through its involvement in the Zn ++ -responsive transcription of ZnT1 and ZnT2 , while simultaneously suppressing the expression of Zip10 [37, 38]

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However, the nascent nature of the nutritional psychiatry field to date means that the existing literature identified in this review is largely comprised of preclinical animal studies

In addition, some of these studies have explored the use of compounds targeting the NRF2 system to reinforce its activity during sleep disturbances