When giving one animal multiple injections, space them out across several inches, or inject the other side of the neck
Novel studies found that GLP-1RAs such as liraglutide, semaglutide and exendin-4 reduces -synuclein aggregation respectively in MPTP (a mitochondrial complex I inhibitor) and 6-OHDA induced PD mice models as well as rat model of -synucleinopathy
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During GLP-1 treatment , maintain regular contact with your healthcare team and report: Any new or worsening anxiety symptoms , including excessive worry, panic attacks, or physical anxiety symptoms Changes in mood , sleep patterns, or appetite beyond expected treatment effects Difficulty coping with side effects such as nausea, which may exacerbate anxiety Concerns about body image or eating behaviours as weight changes occur NICE guidance recommends holistic care for people with diabetes and obesity, recognising the importance of psychological wellbeing
Funding The authors did not receive support from any organization for the submitted work
