The receptor's large, complex binding surface, characteristic of class B GPCRs, was thought to require the extensive contact area that only a peptide could provide
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In addition to cardiometabolic risk factor reduction, their additional effect at the cellular and cytokines levels is likely to contribute to reduction of inflammation, atherosclerosis, and plaque formation
Separately, Pfizer entered a $2.085B deal with YaoPharma (Dec 2025) for a GLP-1 asset, and a $495M deal with Sciwind Biosciences (Feb 2026) to commercialize ecnoglutide in China
In other words, BPC 157 may support the conditions that allow hypertrophy training to continue, but it should not be framed as a direct muscle-growth peptide