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From an endocrine specialists point of view, choosing the right option depends on goals, medical history, side-effect tolerance, and practical issues such as cost and access

If the goal is maximizing glutathione synthesis and the person tolerates NAC well, that route may be worth considering with the understanding that GI side effects could overlap with GLP-1 effects

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After 20 weeks of treatment, DEN mice displayed a notable reduction in body weight compared with control mice, while DEN mice supplemented with GSH or Se exhibited an attenuated decrease in body weight