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By regulating the expression of the pro-invasive molecule alanyl aminopeptidase (Anpep) on the surface of endothelial cells, hepatic invariant-NKT (iNKT)-derived IL-22 modulated endothelial cell permeability and favored the seeding of circulating cancer cells in the liver, promoting CRC liver metastases (144)

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Patients receive Cerebrolysin intravenously daily for ten days duration post-EVT

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The GLOW Blend's 70mg total for C$160 works out to approximately C$2.29/mg across three compounds