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Low selenium consumption has been linked to a higher incidence of thyroid-related disorders such as goiter, autoimmune thyroiditis (AITDs), and hypothyroidism [11]

This phase typically provides the clearest indication of whether the protocol is working for a given individual and condition

For longer term storage, freezing at -20C is recommended to maintain integrity

Common examples include insurance coverage changes, side effects, and availability

Methodological differences, outcome measure variability, incomplete reporting, biological confounders, and overgeneralization of the results made evaluating innovative pharmacological agents challenging