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This study is particularly valuable because using an active comparator controls for many confounding factors

Dedicated constitutional (germline) testing using a DNA and RNA-based platform (Invitae Multi-Cancer+RNA Panel) was performed on whole blood and was negative for all alterations, including in PRKAR1A

As GSTP1 appears not to be expressed in HepG2 cells (Sison-Young et al., 2015), the low activity of CDNB conjugation in lysates from mock-transected cells is most likely due to other GST isoforms (Scharmach et al., 2009)

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The benzyl alcohol component helps inhibit bacterial growth, allowing for multiple withdrawals from a single vial when proper aseptic techniques are followed