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Advances in the understanding of gut hormone physiology particularly their role in appetite regulation, metabolism, and glucose homeostasis - have driven the development of glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) as effective and safe treatments for type 2 diabetes (T2D) and obesity

Topical intestinal aminoimidazole agonists of G-protein-coupled bile acid receptor 1 promote glucagon like peptide-1 secretion and improve glucose tolerance

The insulin receptor: a prototype for dimeric, allosteric membrane receptors

1991 Jun 1;88(11):4656-60