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These advantages are prompting healthcare systems to integrate GLP-1s into first-line or second-line therapy guidelines

Understanding how nutritional strategies and GLP-1 RAs interact with the gut microbial ecosystem may offer novel insights into optimising therapeutic outcomes and mitigating AEs

It exerts its effects through the GLP-1 receptor (GLP-1R), which is found in various cell types, including pancreatic beta cells

Microneedling component of micro-infusion Human outcome Microneedling as collagen induction has a reasonable human base for texture and scar improvement across systematic and narrative reviews, with histology showing increased dermal collagen and elastic fiber and a transient rise in skin permeability that is the rationale for serum delivery

Diabetes Obes Metab 19:2432 Vilsboll T, Christensen M, Junker AE et al (2012) Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials