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More recently, it has petitioned the FDA to block production of compounded semaglutide by placing the ingredient on the Demonstrable Difficulties for Compounding list, which excludes drugs that are too difficult to compound safely

Their primary function is to stimulate insulin secretion, but they do more than that, and the full scope of what they do is central to understanding why GLP-1 receptor agonists have become so significant in clinical practice

Brand medications have manufacturer pricing, insurance rules, coupon terms, and pharmacy benefit structures

They're usually injected and come with high price tags (up to $1,000/month) and a long list of potential side effects, from nausea and bloating to more serious risks like pancreatitis, bone-density loss, and even tumors

GLP-1s are taking up significant fill-finish capacity in the pharmaceutical industry