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A 2021 study published in Gut Microbes examined how Akkermansia muciniphila may influence enteroendocrine cells, which are the cells in the gut lining that produce hormones like GLP-1

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What dysesthesia looks like: Tingling or "pins and needles" sensations, most commonly in hands, feet, or face Altered temperature sensation Burning or prickling sensations Onset typically during dose escalation (weeks 416) but can occur later Severity: Most cases were mild and didn't lead to treatment discontinuation

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