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For instance, it has been shown to promote peripheral nerve regeneration and enhance functional recovery after nerve injury in animal models

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Blood (2003) 101(7):265260.10.1182/blood-2002-05-1300 35 Valdes-FerrerSIRosas-BallinaMOlofssonPSLuBDanchoMEOchaniMet alHMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors