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Br J Pharmacol 179(4):557570 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018a) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial

Semaglutide improves glycemic control by increasing insulin secretion and reducing hepatic glucose output

whilst hepatically metabolised, it does not significantly interact with omeprazole's CYP2C19 pathway

Sies H, Koch OR, Martino E, Boveris A: Increased biliary glutathione disulfide release in chronically ethanol-treated rats