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The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

The heme group of enzymes is very important for endothelial cells because it regulates activities of soluble guanylate cyclases (GCs), nitric oxide synthase (NOS), cytochrome P450 (CYP450), mono-oxigenase, cyclo-oxigenase (COX) and catalase (21, 22)

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Together, these mechanisms help to significantly reduce blood glucose levels while promoting satiety

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