Albanese M, Zagaglia S, Landi D, Boffa L, Nicoletti CG, Marciani MG, et al
The GLP-1R is widely expressed in both central and peripheral tissues, including the brain, heart, and kidney
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Common issues include nausea, diarrhea, abdominal pain, and vomiting, which are typical of GLP-1 agonists
15 The BGA links the enteric nervous system (ENS) and the central nervous system (CNS) via the hypothalamicpituitaryadrenal (HPA) axis, thereby driving the endocrine system to release hormones such as cortisol, which in turn exert bidirectional interactions with the gut immune system