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One of the major pharmacological barriers is the BBB, which restricts the entry of most therapeutic agents into the central nervous system

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We start the patient on the lowest dose, said Ali, and adjust it every 4 weeks

Dehydration and Electrolyte Changes as Contributing Factors Semaglutide-induced nausea and reduced food intake can lead to inadequate hydration and electrolyte depletion, both of which can trigger or worsen muscle cramps and back tension

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