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Cognitive impairment is seen at 7 months of age, and neurofibrillary tangles are absent from this model

Chronic injuries with established dysfunction respond less dramatically than acute injuries

Increase the risk of sagging skin , as rapid weight loss can leave the skin without the underlying support needed to maintain its elasticity, and may not be able to keep up with the reduction in volume underneath

Using it longer means the overall cost will grow compared to medicines used for a short time

Sub-clinical mineral deficiencies can also occur during prolonged wet conditions or stressful periods, such as weaning, when feed intake can be reduced