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As protein oxidative damage and decline in oxidative stress homeostasis occur in the frontal lobe during aging (Cabr et al., 2017) and the frontal lobes exhibit the greatest age effects in the brain (e.g., gray matter reduction and volume loss

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doi: 10.1186/s13048-019-0529-x 15 WangHXuJMLiHChenWHZengXXSunYPet al

At 25 weeks of age, mice were divided into groups receiving daily subcutaneous injections of vehicle, 150 nmol/kg/day salmon calcitonin, or 3 nmol/kg/day Cagrilintide for three weeks