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Am J Physiol (Heart Circ.Physiol.) 262: H14861493, 1992

SHAP analysis identified 24 variables that contributed more than 4% of the regularized TMAO standard deviation (SD) to model outcomes

The intestinal microbial metabolite acetyl l-carnitine improves gut inflammation and immune homeostasis via CADM2

Bruising and swelling usually subside in 2 to 4 weeks

This process ultimately suppresses HSC activation (reducing -SMA expression), inhibits the mRNA expression of type I and III collagen, reduces the production and deposition of ECM, mitigates fibrotic tissue hyperplasia and pseudolobule formation, and thereby reverses liver fibrosis (Wang Q