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This, in part, reflects the challenge and mistrust of the medical establishment, which worsened during the Covid pandemic, but was already showing strong signs of opposition by the wide adoption of supplements (with a very similar lack of supportive data on efficacy and safety) long before 2020

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If pain, range of motion, or function has not moved by week 4, the dose or delivery method needs adjusting rather than extending the same protocol blindly

Massage gently with upward strokes until fully absorbed

That can slow how the dose is used and is a known issue, particularly in women and larger patients where there is more tissue to pass through