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In DECLARE-TIMI58 with dapagliflozin, 4.4% of the patients were using GLP-1RAs at baseline, and dapagliflozin reduced the risks of MACE, HHF, and composite kidney outcomes regardless of baseline GLP-1RA use [49]

Science Kim et al

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While Trulicity has a lower cash price, the difference in weight loss efficacy should be considered when evaluating overall value

In 2011, researchers using non-targeted metabolomics methods found that TMAO was associated with an increased risk of cardiovascular events in subjects