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Studies suggest that Contrave involves pathways within the CNS, particularly regarding the hypothalamus

Although B12 is a water-soluble vitamin (aka youll pee out the excess your bod doesnt use), you still shouldnt add a supplement without a trip to your doctor to test your vitamin levels

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Furthermore, the threshold effect is consistent with the concept that methionine synthase activity may become saturated beyond a certain B12 concentration [17], explaining the diminishing returns observed at higher levels