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How to protect your teeth while on GLP-1s A few consistent habits go a long way toward keeping your smile healthy throughout treatment: Sip water through the day and consider a dentist-recommended dry-mouth rinse or xylitol product Wait about 30 minutes after reflux or nausea before brushing, then brush with a fluoride toothpaste Keep up twice-daily brushing and daily flossing, and dont skip cleanings Limit acidic and sugary drinks that compound enamel stress Read more: Gum Disease and Systemic Health Why you should tell your dentist Letting your dental team know you are on a GLP-1 medication allows us to tailor your care more frequent cleanings if needed, targeted fluoride or remineralizing treatments, and guidance on sedation, since these drugs slow stomach emptying and can affect how some procedures are planned