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November 12 Product: Intercept Pharmaceuticals Ocaliva Indication: Primary biliary cholangitis After initially delaying its decision last month, the FDA on Tuesday declined to give Intercept Pharmaceuticals Ocaliva (obeticholic acid) full approval for primary biliary cholangitis (PBC)

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Notably, the age-related increases in nitration of ECM-bound HGF were predominant on fast IIa and IIx myofibers 32 , corresponding with the fast fiber-preference observed in age-related muscle atrophy and impaired regeneration in humans in which fast IIb fibers are scarce 33,34,35, 39

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