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Optogenetic activation of the neurons triggered immediate meal termination and reduced bout duration and frequency, while neural inhibition prolonged bout duration and increased food intake, showing that the neurons are necessary and sufficient for satiation

It means your timing should depend on your symptoms, dose schedule, health history, and the type of procedure

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The bigger issue is that some people try a supplement like this to self-treat a condition

How GLP-1 Receptors Influence Digestive Health GLP-1 receptors play a multifunctional role in the gut, affecting motility, secretions, immune function, and microbial balance